Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.321


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GABPAchr21_+_271077310.844.0e-05Click!
ELK1chrX_-_475098640.712.2e-03Click!
GABPB1chr15_-_506472750.448.5e-02Click!
ELK4chr1_-_2056007790.283.0e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_38273823 4.747 YRDC
yrdC domain containing (E. coli)
chr7_-_99698278 4.513 NM_182776
 MCM7
minichromosome maintenance complex component 7
chr3_+_180319898 4.426 NM_001042601
NM_133462
 TTC14

tetratricopeptide repeat domain 14

chr4_+_110736636 4.174 NM_018983
NM_032993
 GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr21_-_33984865 4.083 NM_021254
 C21orf59
chromosome 21 open reading frame 59
chr1_-_38273683 3.806 YRDC
yrdC domain containing (E. coli)
chr12_+_120105656 3.741 NM_006253
 PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_38273846 3.655 YRDC
yrdC domain containing (E. coli)
chr7_-_128694823 3.642 TNPO3
transportin 3
chr7_-_2281797 3.415 FTSJ2
FtsJ homolog 2 (E. coli)
chr10_-_43892697 3.343 NM_001098207
 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_-_38273852 3.241 NM_024640
 YRDC
yrdC domain containing (E. coli)
chr6_+_170863420 3.228 NM_001172085
NM_003194
 TBP

TATA box binding protein

chr9_-_138853146 3.158 NM_016172
 UBAC1
UBA domain containing 1
chr7_-_128695118 3.035 TNPO3
transportin 3
chr9_-_138853007 3.026 UBAC1
UBA domain containing 1
chr1_-_222763081 2.992 NM_001201536
NM_005681
NM_139352
 TAF1A


TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa


chrX_-_100603956 2.940 NM_004085
 TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr4_-_159644439 2.932 NM_005038
 PPID
peptidylprolyl isomerase D
chr13_-_46756326 2.908 NM_002298
 LCP1
lymphocyte cytosolic protein 1 (L-plastin)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
5.73 2.51e-02 GO:0022618 ribonucleoprotein complex assembly
5.64 4.84e-04 GO:0042254 ribosome biogenesis
5.62 4.18e-07 GO:0022613 ribonucleoprotein complex biogenesis
5.51 3.45e-02 GO:0071826 ribonucleoprotein complex subunit organization
5.34 1.05e-06 GO:0071843 cellular component biogenesis at cellular level
2.64 2.72e-03 GO:0006396 RNA processing
2.10 2.51e-02 GO:0007049 cell cycle
1.94 2.86e-04 GO:0010467 gene expression
1.93 1.01e-03 GO:0016070 RNA metabolic process
1.84 2.66e-04 GO:0090304 nucleic acid metabolic process
1.65 3.78e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 4.88e-05 GO:0044260 cellular macromolecule metabolic process
1.45 2.19e-03 GO:0043170 macromolecule metabolic process
1.31 3.58e-02 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
3.43 7.11e-07 GO:0005730 nucleolus
2.49 1.51e-02 GO:0030529 ribonucleoprotein complex
2.21 3.48e-02 GO:0044429 mitochondrial part
2.15 3.84e-02 GO:0031967 organelle envelope
2.12 4.89e-02 GO:0031975 envelope
1.98 7.76e-07 GO:0044428 nuclear part
1.95 4.35e-03 GO:0005739 mitochondrion
1.94 4.17e-05 GO:0031981 nuclear lumen
1.92 8.60e-07 GO:0031974 membrane-enclosed lumen
1.90 4.43e-06 GO:0070013 intracellular organelle lumen
1.86 1.14e-05 GO:0043233 organelle lumen
1.61 4.83e-03 GO:0043228 non-membrane-bounded organelle
1.61 4.83e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.58 1.62e-08 GO:0005634 nucleus
1.52 2.76e-03 GO:0032991 macromolecular complex
1.40 7.00e-04 GO:0044446 intracellular organelle part
1.39 6.36e-10 GO:0043231 intracellular membrane-bounded organelle
1.39 7.47e-10 GO:0043227 membrane-bounded organelle
1.38 1.52e-03 GO:0044422 organelle part
1.34 1.76e-09 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
8.84 4.99e-02 GO:0002039 p53 binding
2.16 1.41e-02 GO:0003723 RNA binding
1.29 1.66e-03 GO:0005515 protein binding